手机版 English 帮助中心
外文文献知网节
文献信息节点
基本信息 摘要 关键词 核心评价 相关文献
Journal | [J] 临床医学研究 Volume 5, Issue 3. 2023.
尼日利亚跨河州家庭中儿童粪便和生牛肉中的大肠杆菌 O157 H7 血清型的风险分析和抗生素图谱
作者 : Nfongeh Fuh, Owoseni Christiana, Obande Attah, Upla Peter Uteh, Odonye Dantani, Fadayomi Kolawole, Uchenwa Mercy Ogechi
DOI: 10.12361/2705-0939-05-03-127114
全部来源
获取全文
摘要 / Abstract
这项横断面研究旨在评估尼日利亚南部克罗斯河州部分家庭的儿童粪便和牛肉中的大肠杆菌O157:H7的风险因素和抗 生素图谱。共收集了360份新鲜的家庭牛肉样品和366份儿童腹泻和非腹泻的粪便样品，并使用标准的培养和血清学方法对大 肠杆菌O157:H7进行了检测。证实的大肠杆菌O157: H7分离物使用琼脂盘扩散法进行抗菌素敏感性评估。家庭肉类中大肠杆 菌O157: H7的总阳性样本为76/360（21.11%），而腹泻和非腹泻的粪便样本分别有70/366（19.13%）和5/366（1.37%）阳性 样本。在来自不同家庭的牛肉样本中，以及在腹泻和非腹泻的样本中，观察到的患病率值有显著差异，P<0.05。观察到的风 险因素包括：年龄范围，最高流行值为1-2岁（26.83%）；父母/监护人的职业，最高流行值为农业（25.67%）；主要生活水 源，最高流行值为地表水（28.21%），这些因素对儿童腹泻粪便中的病原体流行率有显著影响（P<0.05）。所有70个腹泻分 离物都对一种或多种抗生素有耐药性，其中四环素（88.6%）和复方新诺明（77.1%）的值最高。这项研究显示，牛肉和一 些人类及环境因素在研究社区的儿童感染大肠杆菌O157:H7的过程中起着至关重要的作用，腹泻粪便是人类二次感染的主要 载体。因此，牛是向人类传播具有多重抗药性的大肠杆菌O157:H7的主要来源，因此有必要对这种病原体进行持续监测，并 实施立法禁止在养牛场滥用抗生素。
关键词 / Keywords
大肠杆菌O157:H7；儿童粪便；牛肉；风险因素；抗生素；尼日利亚
Related articles / 相关文献
相似文献
作者发文
机构发文
关键词分析
相似文献（说明：与本文内容较接近的文献）
  • [1] Griffin, P. M. (1995). Escherichia coli O157:H7 and
  • other Enterohemorrhagic Escherichia coli, P. 739-761. In M. J. Blaser, P. D. Smith, J. I. Rovin, H. B. Greenberg, And R. L. Guerrant (Ed.), Infections of the Gastrointestinal Tract. Raven Press, New York, NY
  • [2] Seibt, F., Filer, G., Gellermann, J., Beutin, L., Ehrih, J. (1995). The Heterogeneity of Haemolytic Uraemic Syndromes
  • in Children and Adults. Nephrologisches Jahresgespräch. Editor: Deutsche Dialysegesellschaft.
  • [3] Mora, A., Blanco, J. E. and Blanco, M. (2005). Antimicrobial resistance of Shiga toxin (verotoxin)- producing
  • Escherichia coli O157:H7 and non-O157 strains isolated from
  • humans, cattle, sheep and food in Spain. Research in Microbiology, 156(7): 793–806. [4] Mead, P. S. and Griffin, P. M. (1998). Escherichia
  • coliO157:H7. Lancet, (35): 1207-1212. [5] Cooley, M. (2007). Incidence and Tracking of
  • Esherichia coli O157:H7 in a major produce production region
  • in California. PLos ONE, 2(11): e1159. [6] Enem, S. I. and Oboegbulem, S. I. (2015). Epidemiology of Verocytotoxigenic Escherichia coli (VTEC)
  • O157 Serotype in Cattle in Federal Capital Territory, Abuja, Nigeria. Journal of Veterinary Medicine and Research, 2(3): 10- 26. [7] Duffy, G. (2006). Emerging pathogenic E. coli. In: Emerging Foodborne Pathogens, M. Yasmine and A. Martin, Eds. Pp. 253–272, CRC. [8] Presterl, E., Zuick, R. H., Reichmann, S., Aichelburg, A., Winkler, S., Kremsner, P. G and Graninger, A(2003). Frequency and Virulence Properties of Diarrhoeagenic Escherichia coli in Children with Diarrhoea in Gabon. American
  • Journal of Tropical Medicine and Hygiene. 69(4):406-410. [9] Nigatu, D., Berhanu, S., Shimelis, M., Yimer, M., and
  • Dinaol, B. (2017). Prevalence and Antimicrobial Susceptibility
  • Pattern of E. coli O157:H7 Isolated from Traditionally
  • Marketed Raw Cow Milk in and around Asosa Town, Western Ethiopia. Veterinary Medicine International, (7): 1-7. [10] Galland J C. (2001). Prevalence, antibiotic
  • susceptibility, and diversity of Escherichia coli O157:H7
  • isolates from a longitudinal study of beef cattle feedlots. Applied and Environmental Microbiology, 67(4):1619-1627. [11] Raji, M. A., Minga, U. and Machangu, R. (2006). Current epidemiological status of enterohaemorrhagic Escherichia coli O157:H7 in Africa,” Chinese Medical Journal, 119(3): 217–222
  • [12] Walsh, C., Duffy, G., O’Mahony, R., Fanning, S., Blair, I. S. and McDowell, D. A. (2006). Antimicrobial resistance in Irish isolates of verocytotoxigenic Escherichia coli
  • (E. coli)-VTEC. International Journal of Food Microbiology, 109(3): 173–178. [13] Reuben, C. R. and Gyar, S. D. (2015). Isolation and
  • Antibiogram of Shiga Toxin-Producing Escherichia coli
  • O157:H7 from Diarrhoeic HIV/AIDS Patients in Lafia, Central
  • Nigeria. International Research Journal of Microbiology, 6(2): 020-026, [14] Meng, J. and Doyle, M. P. (1998). Emerging and
  • evolving microbial foodborne pathogens. Bulletin de L’Institut
  • Pasteur, 96: 151-164. [15] Molbak, K., Mead, P. S. and Griffin, P. M. (2002). Antimicrobial Therapy in Patients with Escherichia coli
  • O157:H7 Infection. Journal of American Medical Association, 288:1014-6. [16] Nfongeh J. F; Epoke, J; Antai, E. E; Ikpeme, E. M;
  • Etim, L. B; Akeh, M. and Ekpiken, S. E. (2014). The Effects of
  • Escherichia coli 0157:H7 lipopolysaccharide (LPS) from human, cattle and poultry isolates on haematological parameters of neonatal albino rats. European Journal of Experimental Biology
  • 4(1):538-542
  • [17] Clinical and Laboratory Standard Institute (CLSI)
  • (2007). Performance Standards for Antimicrobial Susceptibility
  • Testing. Seventeenth Informational Supplement. Approved
  • Standard M100-S17: Wayne, PA. [18] Hiko, A., Asrat, D. and Zewde, G. (2008). Occurrence of Escherichia coli O157:H7 in retail raw meat products in Ethiopia. J Infect Dev Ctries., 2(5):389–393
  • [19] Tizeta, B., Girma, Z., Genene, T., Aklilu, F. and
  • Kaleab, Z. (2014). Escherichia coli O157:H7 in Raw Meat in Addis Ababa, Ethiopia: Prevalence at an Abattoir and Retailers and Antimicrobial Susceptibility. International Journal of Food
  • Contamination, 1(4): 3-8
  • [20] Abong’O, B. O. (2008). Prevalence of Escherichia
  • coli 0157:H7 in water, meat, meat products and vegetables sold
  • in the Eastern Cape Province of South Africa and its impact on
  • the diarrhoeic conditions of HIV/AIDS patients. PhD Thesis University of Port Hare, South Africa. [21] Hajian, S., Rahim, E. & Mommtaz, H., (2011). A 3- year study of E. coli 0157:H7 in cattle, camel, sheep, goat, chicken and beef minced meat. International Conference on Food Engineering and Biotechmology. 9: 162-166
  • [22] Dahiru, M., Uraih, N., Enabulele, S. A. and
  • Shamsudeen, U. (2008). Prevalence of Escherichia coli 0157:H7
  • in fresh and roasted beef in Kano City, Nigeria. Bayero J Pure Appl Sci., 1:39–42
  • [23] McEvoy, J. M., Sheridan, J. J. and McDowell, D. A. (2004). Major pathogens associated with the processing of beef. In: Collins JD (ed) Smulders FJM. Wageningen Academic Publishers, Safety Assurance during Food Processing, pp 57–80.
  • [24] Fard, A. H., Bokaeian, M. and Qureishi, M. E. (2008). Frequency of Escherichia coli O157: H7 in children with
  • diarrhoea in Zahedan, Islamic Republic of Iran. East Mediterr Health J., 14:1022–27
  • [25] . Abdulaziz, H. O., Aminu, M. and Machido, D. A. (2016). Isolation and Characterisation of Esherichia coli O157
  • in Human Stool Samples from Parts of Kaduna Metropolis Nigeria. American Journal of Food Science and Technology, 4(5): 125-128. [26] Olorunshola, I. D., Smith, S. I. and Coker, A. O. (2000). Prevalence of Enterohaemorrhagic Escherichian coli in Patients with Diarrhoea in Lagos, Nigeria. Actapathologica, microbiologica, etimmunologica Scandinavica, 108(11):761- 763. [27] Esumeh, F. I, Isibor, J. O., Egbagbe, I. D. S. (2011). Screening For Escherichia Coli O157:H7 In Diarrheic Patients
  • In Benin City, Nigeria. Journal of Microbiology and
  • Biotechnology Research, 1(4): 1-4. [28] Opintan, J. A., Bishar, R. A., Newman, M. J and
  • Okeke, I. N. (2010). Carriage of diarrheagenic Escherichia coli
  • by older children and adults in Accra Ghana. Trans R Soc Trop
  • Med Hyg., 104(7): 504-506. [29] Umolu, P. I., Omigie, O., Tatfeng, Y., Omorogbe, F. I., Aisabokhale, F. and Ugbodagah, O. P. (2006). Antimicrobial susceptibility and plasmid profiles of Escherichia coli isolates obtained from different human clinical specimens in Lagos – Nigeria. American Journal of Science, 2(4): 70-76. [30] Lim, J. Y., Yoon, J and Hovde, C. J. (2010). A brief overview of Escherichia coli O157:H7 and its plasmid O157. J. Microbiol. Biotechnol., 20 (1):5-14. [31] Marsh, J., MacLeod, A. F., Hanson, M. F., Emmanuel, F. X. S, Frost, J. A and Thomas, A. A. (1992). A restaurant- associated outbreak of E coli O157infection. J. Publ. Health
  • Med., 14: 78-83. [32] WHO. (2000). Global Principles for the Containment of Antimicrobial Resistance in Animals Intended For Food;
  • Report of WHO Consultation With The Participation Of Food
  • and Agriculture Organization of The United Nation and the Office International Des Epizooties, Geneva Switzerland 5- 9
  • June 2000. Department of Communicable Disease Surveillance
  • and Response. [33] Galland, C. J., Hyatt, R. D., Crupper, S. S. and
  • Acheson, W. D. (2001). Prevalence, Antibiotic Susceptibility, and Diversity of E. coli O157:H7 Isolates from a Longitudinal
  • Study of Beef Cattle Feedlots. Journal of Applied and
  • Environmental Microbiology, 67(4):1619-27. [34] Olatoye, I. O. (2010). The Incidence and Antibiotics Susceptibility of Escherichia coli O157:H7 from Beef in Ibadan Municipal, Nigeria. African Journal of Biotechnology, 9(8): 1196-1199. [35] AlHaj, N., Mariana, N. S., Raha, A. R. and Ishak, Z. (2007). Prevalence of Antibiotic Resistance Among Escherichia
  • coli from Different Sources. Malaysia Research Journal of
  • Pharmacology, 1(2): 44-49. [36] Helali, A. (2002). Pharmacologie Fondamentale Et
  • Clinique A L’usage Des Etudiants En Médecine, Santé
  • Collection, ENAG/ Editions. Pp 183. [37] Naik, J. and Desai, P. (2012). Detection of
  • Enterohaemorrhagic Escherichia coli (E. coli O157:H7) and its Drug Resistance Pattern. Journal of Environmental Research
  • and Development, 7(1): 51-55
  • [38] Daini, O. A., Ogbolu, O. D. and Ogunledun, A. (2005). Quinolones resistance and R- Plasmids of some Gramnegative
  • enteric bacilli. African Journal of Clinical and Experimental
  • Microbiology, 6(1): 14-20. [39] Oteo, J., Lazaro, E., de Abjo, F. J., Baquero, F. and
  • Campos, J. (2005). Spanish members of EARSS. Antimicrobialresistant invasive Escherichia coli, Spain. Emerging Infectious Diseases, 11(4): 546- 553. [40] Isibor, J. O., Erhunmwuns, P. I. and Nwobu, G. O. (2003). Antimicrobial susceptibility of clinical isolates of E. coli
  • to six antimicrobial agents. Journal of Applied Basic Science, 1(2):37-40. [41] Schroeder, C. M., Zhao, C., DebRoy, C., Torcolini, J., Zhao, S., White, D. G., Wagner, D. D., McDermott, P. F., Walker, R. D., and Meng, J. (2002). Antimicrobial Resistance of Escherichia coli O157 Isolated from Humans, Cattle, Swine, and Food. Appl. Environ. Microbiol. 68 (2): 576–581
  • [42] Reuben, C. R. and Owuna, G. (2013). Antimicrobial
  • Resistance Patterns of Escherichia coli O157:H7 from Nigerian Fermented Milk Samples in Nasarawa State, Nigeria. Int. J. Pharmaceutical Sci. Invent., 2(3): 38-44. [43] Mincey, B. A. and Parkulo, M. A. (2001). Antibiotic prescribing practices in a teaching clinic: comparison of resident and staff physicians. Southern Med. J., 94(4): 365 - 369. [44] Granizo, J. J., Aguilar, L., Casal, J., Dal-Re, R and
  • Baquero, F. (2000). Streptococcus pyrogenes resistance to
  • erythromycin in relation to macrolide consumption in Spain
  • (1986-1997). J. Antimicrob. Chemother., 46: 959 - 964. [45] Chandran, A. (2008). India Prevalence of Multiple Drug Resistant Escherichia coli Serotypes in a Tropical Estuary, India., Microb. Environ., 23( 2):153-158. [46] Zinnha, M. A. (2008). Bangladesh, Drug sensitivity
  • pattern of Escherichia coli isolated from samples of different
  • Biological and environmental sources, Bangl. J. Vet. Med., 6(1): 13-18
  • [47] Chattopadhyay, U. K., Gupta, S. and Dutta, S. (2010). Search for shiga toxin producing Escherichia coli (STEC)
  • including 0157: H7 strains in and around Kolkata., Ind. J. Med. Microbiol, 21(1), 17-20. [48] Tesfaye, G., Astrat, D., Woldeamanuel, Y. and Gizaw, M. (2009). Microbiology of discharging ears in Ethiopia. Asian Pacific Journal of Tropical Medicine, 2(91): 60-67
  • [49] Abebe, M., Hailelule, A., Abrha, B., Nigus, A., Birhanu, M., Adane, H., Genene, T., Daniel, H., Getachew, G., Merga, G. and Haftay, A. (2014). Antibiogram of Escherichia
  • coli strains from food of bovine origin in selected Woredas of
  • Tigray, Ethiopia. Journal of Bacteriology Research, 6(3): 17-22. [50] Wariso, B. A. and Ibe, S. N. (2006). Bacteriology of chronic discharging ears in Port Harcourt, Nigeria. West
  • African Journal of Medicine, 25: 219-222.
《中国学术期刊(光盘版)》电子杂志社有限公司 KDN平台基础技术由KBASE 11.0提供
© 2014-2018中国知网(CNKI) 京公网安备11010802020460号 经营性网站备案信息 互联网出版许可证 新出网证(京)字271号 京ICP证040431号