手机版 English 帮助中心
外文文献知网节
文献信息节点
基本信息 摘要 关键词 核心评价 相关文献
Journal | [J] 医学研究 Volume 5, Issue 24. 2023.
Nrf2信号通路在外阴阴道念珠菌病中致病机制的研究进展
作者 : 廖 晴君
DOI: 10.12361/2661-3603-05-24-154287
全部来源
获取全文
摘要 / Abstract
摘要：外阴阴道念珠菌病是一种由白念珠菌机会性感染引起的皮肤黏膜疾病，念珠菌的毒力因素､宿主免疫及阴道微生物群是外阴阴道念珠菌病主要的发病机制｡Nrf2信号通路是细胞抗氧化应激重要的免疫调节通路｡该文以Nrf2通路在念珠菌性阴道炎发病机制中的抗氧化应激和激活自噬作用进行综述，旨在研究Nrf2信号通路与外阴阴道念珠菌病发病机理间的关系，有望为外阴阴道念珠菌病精准治疗提供新的研究方向｡
关键词 / Keywords
关键词：Nrf2信号通路;外阴阴道念珠菌病;白念珠菌;致病机制
Related articles / 相关文献
相似文献
作者发文
机构发文
关键词分析
相似文献（说明：与本文内容较接近的文献）
  • [1]Phillips NA, et al. Ibrexafungerp for the treatment of
  • vulvovaginal candidiasis: design, development and place in therapy.
  • Drug Des Devel Ther. 2023 Feb 7;17:363-367.
  • [2]Collins LM, et al. Prognosis and long-term outcome of women
  • with idiopathic recurrent vulvovaginal candidiasis caused by Candida
  • albicans. J Low Genit Tract Dis. 2020 Jan;24(1):48-52.
  • [3]Chen W, et al. Transferrin-targeted cascade nanoplatform for
  • Inhibiting transcription factor nuclear factor erythroid 2-related
  • factor 2 and enhancing ferroptosis anticancer therapy. ACS Appl
  • Mater Interfaces. 2023 Jun 21;15(24):28879-28890.
  • [4]Bamford CV, et al. Functional regions of Candida albicans
  • hyphal cell wall protein Als3 that determine interaction with the oral
  • bacterium Streptococcus gordonii. Microbiology (Reading). 2015
  • Jan;161(Pt 1):18-29.
  • [5]Alves CT, et al. Candida albicans promotes invasion and
  • colonisation of Candida glabrata in a reconstituted human vaginal
  • epithelium. J Infect. 2014 Oct;69(4):396-407.
  • [6]d'Enfert C, et al. The impact of the Fungus-Host-Microbiota
  • interplay upon Candida albicans infections: current knowledge and
  • new perspectives. FEMS Microbiol Rev. 2021 May 5;45(3):fuaa060.
  • [7]Rodríguez-Cerdeira C, et al. Pathogenesis and clinical
  • relevance of Candida biofilms in vulvovaginal candidiasis. Front
  • Microbiol. 2020 Nov 11;11:544480.
  • [8]Ebrahimpour A, et al. Esomeprazole attenuates inflammatory
  • and fibrotic response in lung cells through the MAPK/Nrf2/HO1
  • pathway. J Inflamm (Lond). 2021 May 19;18(1):17.
  • [9]Dodson M, et al. NRF2 plays a critical role in mitigating lipid
  • peroxidation and ferroptosis. Redox Biol. 2019 May;23:101107.
  • [10]Loboda A, et al. Role of Nrf2/HO-1 system in development,
  • oxidative stress response and diseases: an evolutionarily conserved
  • mechanism. Cell Mol Life Sci. 2016 Sep;73(17):3221-47.
  • [11]Lopes JP, et al. Evasion of Immune Surveillance in low
  • oxygen environments enhances candida albicans Virulence. mBio.
  • 2018 Nov 6;9(6):e02120-18.
  • [12]Rossi DCP, et al. Candida albicans FRE8 encodes a
  • member of the NADPH oxidase family that produces a burst of ROS
  • during fungal morphogenesis. PLoS Pathog. 2017 Dec
  • 1;13(12):e1006763.
  • [13]Tang Z, et al. Nrf2 drives oxidative stress-induced
  • autophagy in nucleus pulposus cells via a Keap1/Nrf2/p62 feedback
  • loop to protect intervertebral disc from degeneration. Cell Death Dis.
  • 2019 Jul 1;10(7):510.
  • [14]Lee JM, et al. NXP031 Improves cognitive impairment in a
  • chronic cerebral hypoperfusion-induced vascular dementia rat model
  • through Nrf2 signaling. Int J Mol Sci. 2021 Jun 11;22(12):6285.
  • [15]Akimoto-Gunther L, et al. Highlights regarding host
  • predisposing factors to recurrent vulvovaginal candidiasis: chronic
  • stress and reduced antioxidant capacity. PLoS One. 2016 Jul
  • 14;11(7):e0158870.
  • [16]Hall RA, et al. CO(2) acts as a signaling molecule in
  • populations of the fungal pathogen Candida albicans. PLoS Pathog.
  • 2010 Nov 18;6(11):e1001193.
  • [17]史远哲,吴媛媛,肖风丽.自噬在特应性进程中的研究进
  • 展[J].皮肤科学通报,2022,39(05):474-478.
《中国学术期刊(光盘版)》电子杂志社有限公司 KDN平台基础技术由KBASE 11.0提供
© 2014-2018中国知网(CNKI) 京公网安备11010802020460号 经营性网站备案信息 互联网出版许可证 新出网证(京)字271号 京ICP证040431号