急性心肌梗死急诊PCI术后早期应用新活素的临床疗效分析 Clinical analysis of early application of neovorin after emergency PCI for acute myocardial infarction

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陈登, Deng Chen, 张修泽

石河子大学医学院第一附属医院新内二科, Department 2, Xinnei, First Affiliated Hospital of Shihezi University Medical College, 石河子大学医学院第一附属医院新内二科)Xiuze Zhang(Department 2, Xinnei, First Affiliated Hospital of Shihezi University Medical College

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摘要：目的：分析急性心肌梗死患者急诊PCI术后早期应用新活素的临床效果。方法：抽取2019年1月-2021年1月期间在我院急诊行PCI治疗的急性心肌梗死患者84例作为研究对象，以数字随机法对其进行分组，接受常规治疗的为对照组（n=42），在常规治疗的基础上早期应用新活素治疗的为研究组（n=42），随访时间为6个月，对比两组患者B型钠尿肽（NT-proBNP）水平、心功能指标（包括LVST、LVEF、LVD和CI）、心血管不良事件发生率及患者和家属对治疗效果的满意度。结果：（1）治疗前两组患者NT-proBNP水平对比无明显差异，（P＞0.05），治疗后研究组患者BNP水平明显低于对照组，（P＜0.05）。（2）治疗前两组患者各项心功能指标对比均无明显差异，治疗后研究组患者LVST、LVD检测量结果均明显低于对照组，LVEF、CI检测结果明显高于对照组，（P＜0.05）。（3）随访6个月，研究组患者心血管不良事件发生率明显比对照组患者低，（P＜0.05）。（4）研究组患者及家属对治疗效果的满意度明显比对照组患者及家属高，（P＜0.05）。结论：对于行PCI治疗的急性心肌梗死患者而言，术后早期应用新活素可显著改善患者心功能、降低患者再发心血管不良事件的风险，值得推广。 Objective: To analyze the clinical effect of early application of neovorin in patients with acute myocardial infarction after emergency PCI.Methods: Eighty-four patients with acute myocardial infarction (AMI) who underwent PCI in our hospital from January 2019 to January 2021 were randomly divided into control group (n=42) and routine treatment group (n=42). The patients who were treated with neovirin at early stage were followed up for 6 months.Results:(1) There was no significant difference in the level of NT-proBNP between the two groups before treatment (P >0.05). After treatment, the level of BNP in the study group was significantly lower than that in the control group (P

关键词：

急诊PCI；急性心肌梗死；B型脑钠肽；心功能；心血管不良事件 Emergency PCI; acute myocardial infarction; type B brain natriuretic peptide; cardiac function; cardiovascular adverse events

Universe Scientific Publishing

ISSN：2705-098X

年,卷(期)：2022,4(1)