光控水凝胶负载太子参多糖对大鼠糖尿病溃疡创面修复 作用研究

赵 月
深圳市光明区中医药传承发展研究院

摘要

目的：本研究制备了一种具有光控性并负载太子参多糖的水凝胶，进一步研究了负载太子参水凝胶的理化性
能和溃疡创面修复效果。方法：以 PolyCBNA 和明胶为主要原料制备光控水凝胶，通过微观结构、药物释放量和体内动物
实验对其进行分析评估。结果：PolyCBNA/ 明胶 / 太子参多糖结构更紧密，说明，加入太子参多糖后，能改变水凝胶的微
观结构。而24时，太子参多糖的释放量达到47%。动物模型修复效果更证实表明负载太子参多糖的水凝胶有效促进伤口愈合。
结论：PolyCBNA/ 明胶 / 太子参多糖具有良好的光控性、释药性和修复效果。

关键词

光控水凝胶；太子参多糖；糖尿病；修复

参考

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