血管纹对年龄相关性听力损失发病机制中的作用

王 珊珊, 谌 　容, 洪 　玉
杭州师范大学公共卫生学院

摘要

年龄相关性听力损失（Age-related hearing loss, ARHL）是由内耳异常引起的人类常见感觉障碍。血管纹（stria
vascularis，SV）是一种主要的耳蜗结构，可以独立退化并影响听力。本文旨在综述血管纹与年龄相关性听力损失关系的研
究进展，重点关注在不同病因下血管纹的功能障碍及所致年龄相关性听力损失的文献，这些病因包括氧化应激与炎症、线
粒体功能障碍、血管损伤、基因缺失等方面，尝试从细胞和分子生物学水平上探索其机制。

关键词

年龄相关性听力损失；血管纹；线粒体；氧化应激；血管损伤

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