脐血气对新生儿呼吸窘迫综合征的预测性研究

王 瑞, 刘 杰波
深圳市罗湖区人民医院新生儿科

摘要

背景：新生儿出生时有酸血症会增加发病率和死亡率，预示新生儿有窒息缺氧过程。方法：收集本院 2019 年 6 月至 12 月住院分娩的病例，纳入标准是足月儿、适于胎龄儿，Apgar评分5min时＞7分，脐血气pH < 7.4, BE <-8 mmol/l, lactate > 6 mmol/l.，评价血气值预测呼吸窘迫综合征。结果：704 例新生儿被纳入实验组，脐血气PH值与呼吸窘迫综合征有关联(χ 2 (1) = 10.078,OR(95% CI):3.8 ×10 -4 (2.9 ×10 -6 –0.052)；p<0.05)，ROC 曲线分析分割点是7.11，敏感性、特异性分别是69%、62%。结论：脐血气可作为早期识别新生儿RDS的指标，PH＜7.11是发生RDS的危险因素，低体温和低血糖也是发生RDS的危险因素。此外，PH值、BE值、乳酸和低体温可作为预测入住NICU 的指标。

关键词

新生儿重症监护室；脐带血气分析；P H 值；B E 值；乳酸

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