运动预防和改善阿尔茨海默病的研究进展
摘要
AD的危险因素降低AD的发生和发展,改善健康老年人、轻度认知障碍乃至AD患者的认知功能;另一方面,运动
强度和方式的不同也会带来不同的效果。鉴于此,制定合理的个性化运动运动干预措施,才有望获得预期的AD防治
效果。
关键词
全文:
PDF参考
[1]ScheltensP,DeStrooperB,KivipeltoM,HolstegeH,
ChételatG,TeunissenCE,etal.Alzheimer'sdisease.The
Lancet.2021;397(10284):1577-90.
[2]ValenzuelaPL,Castillo-GarciaA,MoralesJS,dela
VillaP,HampelH,EmanueleE,etal.Exercisebenefitson
Alzheimer'sdisease:State-of-the-science.AgeingResRev.
2020;62:101108.
[3]SmithJC,NielsonKA,WoodardJL,SeidenbergM,
DurgerianS,HazlettKE,etal.Physicalactivityreduces
hippocampalatrophyineldersatgeneticriskforAlzheimer's
disease.FrontAgingNeurosci.2014;6:61.
[4]SobolNA,DallCH,HoghP,HoffmannK,Frederiksen
KS,VogelA,SiersmaV,WaldemarG,HasselbalchSG,BeyerN:ChangeinFitnessandtheRelationtoChangeinCognition
andNeuropsychiatricSymptomsAfterAerobicExercisein
PatientswithMildAlzheimer'sDisease.JAlzheimersDis
2018,65(1):137-145.
[5]OkamotoY,YamamotoT,KalariaRN,Senzaki
H,MakiT,HaseY,KitamuraA,WashidaK,YamadaM,
ItoHetal:Cerebralhypoperfusionacceleratescerebral
amyloidangiopathyandpromotescorticalmicroinfarcts.Acta
Neuropathol2012,123(3):381-394.
[6]SattlerC,EricksonKI,ToroP,SchroderJ:Physical
fitnessasaprotectivefactorforcognitiveimpairmentina
prospectivepopulation-basedstudyinGermany.JAlzheimers
Dis2011,26(4):709-718.
[7]KurzA,PohlC,RamsenthalerM,SorgC:Cognitive
rehabilitationinpatientswithmildcognitiveimpairment.IntJ
GeriatrPsychiatry2009,24(2):163-168.
[8]EtgenT,SanderD,HuntgeburthU,PoppertH,
ForstlH,BickelH:Physicalactivityandincidentcognitive
impairmentinelderlypersons:theINVADEstudy.ArchIntern
Med2010,170(2):186-193.
[9]OgohS,AinsliePN:Cerebralbloodflowduring
exercise:mechanismsofregulation.JApplPhysiol(1985)
2009,107(5):1370-1380.
[10]SmithPJ,BlumenthalJA,HoffmanBM,CooperH,
StraumanTA,Welsh-BohmerK,BrowndykeJN,Sherwood
A:Aerobicexerciseandneurocognitiveperformance:ametaanalyticreviewofrandomizedcontrolledtrials.Psychosom
Med2010,72(3):239-252.
Refbacks
- 当前没有refback。