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运动预防和改善阿尔茨海默病的研究进展

卢 怡睿, 梁 婧, 柳 溪语, 燕 宇飞, 张 天颖
西安医学院基础与转化医学研究所

摘要


本文对运动防治阿尔茨海默病(Alzheimer’sDiseases;AD)的作用进行综述。一方面,运动能够通过影响
AD的危险因素降低AD的发生和发展,改善健康老年人、轻度认知障碍乃至AD患者的认知功能;另一方面,运动
强度和方式的不同也会带来不同的效果。鉴于此,制定合理的个性化运动运动干预措施,才有望获得预期的AD防治
效果。

关键词


阿尔茨海默病;运动;心肺健康;血管健康

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参考


[1]ScheltensP,DeStrooperB,KivipeltoM,HolstegeH,

ChételatG,TeunissenCE,etal.Alzheimer'sdisease.The

Lancet.2021;397(10284):1577-90.

[2]ValenzuelaPL,Castillo-GarciaA,MoralesJS,dela

VillaP,HampelH,EmanueleE,etal.Exercisebenefitson

Alzheimer'sdisease:State-of-the-science.AgeingResRev.

2020;62:101108.

[3]SmithJC,NielsonKA,WoodardJL,SeidenbergM,

DurgerianS,HazlettKE,etal.Physicalactivityreduces

hippocampalatrophyineldersatgeneticriskforAlzheimer's

disease.FrontAgingNeurosci.2014;6:61.

[4]SobolNA,DallCH,HoghP,HoffmannK,Frederiksen

KS,VogelA,SiersmaV,WaldemarG,HasselbalchSG,BeyerN:ChangeinFitnessandtheRelationtoChangeinCognition

andNeuropsychiatricSymptomsAfterAerobicExercisein

PatientswithMildAlzheimer'sDisease.JAlzheimersDis

2018,65(1):137-145.

[5]OkamotoY,YamamotoT,KalariaRN,Senzaki

H,MakiT,HaseY,KitamuraA,WashidaK,YamadaM,

ItoHetal:Cerebralhypoperfusionacceleratescerebral

amyloidangiopathyandpromotescorticalmicroinfarcts.Acta

Neuropathol2012,123(3):381-394.

[6]SattlerC,EricksonKI,ToroP,SchroderJ:Physical

fitnessasaprotectivefactorforcognitiveimpairmentina

prospectivepopulation-basedstudyinGermany.JAlzheimers

Dis2011,26(4):709-718.

[7]KurzA,PohlC,RamsenthalerM,SorgC:Cognitive

rehabilitationinpatientswithmildcognitiveimpairment.IntJ

GeriatrPsychiatry2009,24(2):163-168.

[8]EtgenT,SanderD,HuntgeburthU,PoppertH,

ForstlH,BickelH:Physicalactivityandincidentcognitive

impairmentinelderlypersons:theINVADEstudy.ArchIntern

Med2010,170(2):186-193.

[9]OgohS,AinsliePN:Cerebralbloodflowduring

exercise:mechanismsofregulation.JApplPhysiol(1985)

2009,107(5):1370-1380.

[10]SmithPJ,BlumenthalJA,HoffmanBM,CooperH,

StraumanTA,Welsh-BohmerK,BrowndykeJN,Sherwood

A:Aerobicexerciseandneurocognitiveperformance:ametaanalyticreviewofrandomizedcontrolledtrials.Psychosom

Med2010,72(3):239-252.


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