中风的病理生理学和治疗：现状和未来展望

凯吉 栗子, 登戈 耶丝
病理研究中心

摘要

中风是全球第二大死亡原因，也是导致残疾的主要原因。中风的患病率在发展中国家最高，其中缺血性中
风是最常见的类型。我们对中风的病理生理学和导致缺血性损伤的潜在机制的理解取得了相当大的进展。中风治疗
主要侧重于恢复大脑的血流和治疗中风引起的神经损伤。最近的临床试验缺乏成功导致动物模型的显着改进、重点
驱动的研究设计和新技术在中风研究中的使用。同时，尽管在中风管理方面取得了进展，但中风后护理对家庭、医
疗保健系统和经济产生了重大影响。临床前和临床护理的改进可能是中风治疗、康复、康复和预防成功的基础。在
这篇综述中，我们重点关注中风的病理生理学、治疗靶点识别的主要进展以及中风研究的最新趋势。

关键词

中风；病理生理学；治疗；神经功能缺损；康复；康复

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