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有氧运动对D-半乳糖和AlCl3诱导的肝脂肪变性的影响小家鼠C57BL6J

RichoRyantoRaharjo 1, VeronikaMariaSidharta 2, CyprianusMurtono 3
1、AtmaJaya天主教大学医学与健康科学学院
2、AtmaJaya天主教大学医学与健康科学学院组织学系
3、AtmaJaya天主教大学医学与健康科学学院组织病理学系

摘要


21世纪,久坐的习惯和食用铝箔包装的焦糖食品,使身体处于氧化状态。关于有氧运动及其对炎症和氧化应激的影响存在不同意见。本研究旨在比较给予有氧运动组与未给予D-半乳糖和AlCl3诱导后的肝脏组织学模式:本研究采用实验方法,使用注射了MusmusculusC57BL/的两组D-半乳糖(90mg/kg体重)和AlCl3(40mg/kg体重)。对照组只注射了这些物质。有氧组每天游泳30分钟(每周6天)。处死后肝脏标本行HE染色,评价胆管增殖和脂肪变性变化。与对照组相比,有氧组的胆管增殖(p=0.043)和脂肪变性变化(p=0.043)存在显着差异。每周6天进行30分钟的有氧运动显示出更多的胆管增殖和增加的脂肪变性变化。

关键词


MusmusculusC57BL/6J;有氧运动;D-半乳糖;AlCl3

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参考


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