醒后卒中危险因素分析

张 媛, 陈 丽娅, 赵 振强
海南医学院第一附属医院神经内科

摘要

目的:探讨醒后卒中发病的危险因素及其不同亚型与相关危险因素的关系｡方法:收集2021年11月至2022年10月就诊于海南医学院第一附属医院神经内科的急性缺血性脑卒中(ASI)患者,根据发病时间,将所收集到的病例分为醒后卒中组(WUS)和非醒后卒中组(NWUS),收集各组患者的临床资料,包括人口统计学特征､既往病史､危险因素､实验室检查指标､NIHSS评分､TOAST分型､影像学资料等临床资料,比较两组间的差异｡结果:根据纳入和排除标准,最终纳入272例患者,其中醒后卒中组64例,非醒后卒中组208例｡分析发现,WUS组与NWUS组间性别､高血压､糖尿病､高脂血症､房颤史､冠心病史､既往卒中史､入院随机血糖､肌酐､尿酸､甘油三酯､高密度脂蛋白､脂蛋白a､同型半胱氨酸､糖化血红蛋白组间差异均无统计学意义(P>0.05);WUS组年龄､吸烟人数低于NWUS组,低密度脂蛋白水平､胆固醇水平水平及白蛋白水平高于NWUS组,差异有统计学意义(P<0.05)｡多因素Logistic回归分析显示:吸烟､低密度脂蛋白在模型中均有统计学意义(P<0.05),且均为影响醒后卒中的危险因素｡结论:具有吸烟史､更高水平低密度脂蛋白的患者更易发生醒后卒中｡

关键词

醒后卒中;危险因素;临床特征

参考

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