肥胖或超重成年人间歇性禁食的研究进展

乔 通¹, 黄 俊玲²
1、右江民族医学院
2、右江民族附属医院全科医学科

摘要

随着生活方式的变化和食物供应的改变,肥胖问题不断加剧,因此寻找有效的､可持续的干预方法变得至关重要｡其中,间歇性禁食对超重或肥胖患者具有降低体重､血糖,改善血脂等生化指标的作用优势,因此,开展间歇性禁食对超重或肥胖患者的研究具有重要意义｡本文就不同类型的间歇性禁食方案对超重或肥胖成年人群的干预效果､依从性及安全性等方面的最新研究进展进行综述,以期为超重或肥胖成年人减重,控制或延缓慢性病的发生发展提供新思路｡

关键词

肥胖;超重;间歇性禁食;饮食

参考

[1]Anonymous.Worldobesityatlas2023[EB/OL].(2023-03-04)[2023–03–04].https://www.worldobesityday.org/resources/entry/world-obesity-atlas-2023.[2]PanX-F,WangL,PanA.Epidemiologyanddeterminantsofobesityinchina[J].TheLancetDiabetes&Endocrinology,2021,9(6):373–392.[3]St-OngeM-P,ArdJ,BaskinML,etal.Mealtimingandfrequency:implicationsforcardiovasculardiseaseprevention:ascientificstatementfromtheamericanheartassociation[J/OL].Circulation,2017,135(9).[4]VaradyKA,CienfuegosS,EzpeletaM,etal.Cardiometabolicbenefitsofintermittentfasting.[J].AnnualReviewofNutrition,2021,41:333–361.[5]LiuD,HuangY,HuangC,etal.Calorierestrictionwithorwithouttime-restrictedeatinginweightloss[J].NewEnglandJournalofMedicine,2022,386(16):1495–1504.[6]SchroderJD,FalquetoH,MânicaA,etal.Effectsoftime-restrictedfeedinginweightloss,metabolicsyndromeandcardiovascularriskinobesewomen[J].JournalofTranslationalMedicine,2021,19(1):3.[7]HeadlandML,CliftonPM,KeoghJB.Impactofintermittentvs.continuousenergyrestrictiononweightandcardiometabolicfactors:a12-monthfollow-up[J].InternationalJournalofObesity(2005),2020,44(6):1236–1242.[8]TrepanowskiJF,KroegerCM,BarnoskyA,etal.Effectofalternate-dayfastingonweightloss,weightmaintenance,andcardioprotectionamongmetabolicallyhealthyobeseadults:arandomizedclinicaltrial[J].JAMAInternalMedicine,2017,177(7):930–938.[9]VaradyKA,BhutaniS,ChurchEC,etal.Short-termmodifiedalternate-dayfasting:anoveldietarystrategyforweightlossandcardioprotectioninobeseadults[J].TheAmericanJournalofClinicalNutrition,2009,90(5):1138–1143.[10]HeadlandML,CliftonPM,KeoghJB.Effectofintermittentcomparedtocontinuousenergyrestrictiononweightlossandweightmaintenanceafter12monthsinhealthyoverweightorobeseadults[J].InternationalJournalofObesity(2005),2019,43(10):2028–2036.[11]JamshedH,BeylR,DellaMannaD,etal.Earlytime-restrictedfeedingimproves24-hourglucoselevelsandaffectsmarkersofthecircadianclock,aging,andautophagyinhumans[J].Nutrients,2019,11(6):1234.[12]ChairSY,CaiH,CaoX,etal.Intermittentfastinginweightlossandcardiometabolicriskreduction:arandomizedcontrolledtrial[J].TheJournalofNursingResearch:JNR,2022,30(1):e185.[13]GabelK,KroegerCM,TrepanowskiJF,etal.Differentialeffectsofalternate-dayfastingversusdailycalorierestrictiononinsulinresistance.[J].Obesity(SilverSpring,Md.),2019,27(9):1443–1450.[14]HoddyKK,KroegerCM,TrepanowskiJF,etal.Safetyofalternatedayfastingandeffectondisorderedeatingbehaviors.[J].NutritionJournal,2015,14:44.