运动介导肠道菌群防治2型糖尿病的研究进展

陈 英豪¹, 葛 贝贝², 岳 风杉³
1、信阳航空职业学院
2、武汉体育学院
3、西北工业大学体育部

摘要

2型糖尿病是一种严重而常见的慢性非传染性疾病,2型糖尿病及其并发症已经成为世界范围内增长最快地
的重大公共卫生问题之一。运动是治疗和预防2型糖尿病的非药物措施之一,能够有效调节2型糖尿病的糖脂代谢水
平和幸福指数。人类的肠道中蕴藏着数以亿计的细菌,构成了一个复杂而动态平衡的生态系统,称为肠道微生物组
群也就是肠道菌群。肠道菌群作为中介系统,运动能介导肠道菌群防治慢性疾病,已成为研究热点。而2型糖尿病
患者的肠道菌群的组成和功能与正常人异常,提示运动、2型糖尿病以及肠道菌群三者之间存在一定的相关性。综述
运动对2型糖尿病的影响、肠道菌群与2型糖尿病的交互作用和运动介导肠道菌群预防和治疗2型糖尿病的可能分子
机制,探索运动通过调控2型糖尿病患者肠道菌群的组成和功能防治2型糖尿病的可能性,进一步完善运动调节2型
糖尿病的分子作用机制。

关键词

运动;2型糖尿病;肠道菌群;机制;综述

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