肿瘤相关成纤维细胞在乳腺癌微环境中的研究进展

贺 蒲星, 吴 耀禄
延安大学附属医院腺体血管外科

摘要

乳腺癌的发病率逐年上升。乳腺癌的生物学行为不仅取决于肿瘤自身，肿瘤微环境在乳腺癌的发生发展中
也扮演着至关重要的角色。肿瘤相关成纤维细胞是肿瘤微环境中的重要成分，通过分泌生长因子、趋化因子等参与
肿瘤的生长、侵袭与转移。

关键词

乳腺癌；肿瘤微环境；肿瘤相关成纤维细胞

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