GE11肽的抗肿瘤作用研究进展

陈 星宇, 刘 爽, 侯 雪, 李 嘉玮, 阎 雪莹
黑龙江中医药大学药学院

摘要

GE11是以高亲和力和选择性特异性结合EGFR受体的小分子多肽，其具有相对分子质量小、免疫原性低、易扩散及靶向性高等优势。此外，GE11缀合的纳米粒子增强药物在肿瘤中的蓄积等优点，使得其在生物医学领域，尤其是肿瘤的治疗等方面得到了较为广泛的应用。本文对GE11在癌症治疗中的应用进行总结，这些研究进展揭示了GE11肽在癌症治疗领域的巨大潜力。

关键词

GE11；抗肿瘤作用；表皮生长因子受体；药物靶向

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