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超声引导下前锯肌平面阻滞——用于乳腺癌改良根治术的镇痛效果观察 Ultrasound-guided anterior serratus muscle block——Observation on analgesic effect of modified radical mastectomy

张 梁1, Liang Zhang2, 邵 新峰3, Xinfeng Shao4
1、承德医学院
2、Chengde Medical College
3、保定市第一中心医院麻醉科
4、Department of Anesthesiology, Baoding First Central Hospital

摘要


目的:观察超声引导下前锯肌平面阻滞(SAPB)用于乳腺癌改良根治术中的镇痛效果。方法:选择择期行单侧乳腺癌改良根治术的患者60例随机分为两组:SAPB组(S组,n=30)和全身麻醉组(A组,n=30)。S组行超声引导下SAPB阻滞,术侧注射0.25%罗哌卡因30ml,待确定阻滞起效及平面固定后行全麻诱导,记录术前、术中、术后相关数据。比较围术期麻醉效果差异。结果:与A组比较,S组在术中各个时点的平均动脉压(MAP)和心率(HR)均降低(P<0.05);术中麻醉药物总消耗量减少(P<0.05);术后48h内各时点的静态VAS评分与术后12h内各时点的动态VAS评分均降低(P<0.05),镇痛满意度评分提高(P<0.05)。结论:对于行乳腺癌改良根治术的患者,超声引导下SAPB可有效控制患者术中及术后早期急性疼痛情况,使围术期镇痛效果更完善,促进其快速康复。 Objective: To observe the analgesic effect of anterior serratus muscle block (SAPB) guided by ultrasound in modified radical mastectomy.Methods:60 patients undergoing modified radical mastectomy were randomly divided into two groups: SAPB group (S group, n=30) and general anesthesia group (A group, n=30).SAPB block was performed under the guidance of ultrasound in group S, and 0.25% ropivacaine (30 ml) was injected into the operation side. After the onset of block and plane fixation, general anesthesia induction was performed. Relevant data before, during and after operation were recorded.To compare the effect of anesthesia in perioperative period.Results: Compared with group A, the mean arterial pressure (MAP) and heart rate (HR) of group S decreased at each time point during operation (P <0.05), the total consumption of anesthetic drugs decreased during operation (P <0.05), the static VAS score at each time point within 48 hours after operation and the dynamic VAS score at each time point within 12 hours after operation decreased (P <0.05), and the analgesia satisfaction score increased (P <0.05).Conclusion: For the patients undergoing modified radical mastectomy, SAPB guided by ultrasound can effectively control the acute pain during and early after operation, improve the perioperative analgesia effect and promote the rapid recovery.

关键词


乳腺癌;前锯肌阻滞;改良根治术;术后镇痛 Breast cancer; anterior serratus muscle block; modified radical operation; postoperative analgesia



参考


[1] Richebé P, Capdevila X, Rivat C. Persistent Postsurgical Pain: Pathophysiology and Preventative Pharmacologic Considerations[J].Anesthesiology,2018,129(3):590-607. [2] Brackstone M.A review of the literature and discussion:establishing a consensus for the definition of post-mastectomy pain syndrome to provide a standardized clinical and research approach[J]. Canadian Journal of Surgery, 2016, 59(5):294-295. [3] Blanco R, Parras T, McDonnell JG, et al. Serratus plane block: a novel ultrasound‐guided thoracic wall nerve block[J]. Anaesthesia, 2013, 68(11):1107-1113. [4] 谭敬,吕瑞兆,严军,朱宇麟,周荣胜,景桂霞.超声引导下胸部神经阻滞在乳腺癌改良根治术后多模式镇痛中的应用[J].临床麻醉学杂 志,2017,33(08):747-750. [5] 孙佳昕,田婕,俞卫锋.阿片系统对乳腺癌生长和转移的影响[J].上海医学,2019,(04):252-256. [6] 曾晓平,施宏,吴玮,杜荣,张熙若,吕欣.超声引导下前锯肌平面阻滞的研究进展[J].临床麻醉学杂志,2021,37(09):991-993. [7] Xuan W, Hankin J, Zhao H,et al. The potential benefits of the use of regional anesthesia in cancer patients[J].International Journal of Cancer,2015,137(12):2774-2784. [8] 江文杰,韩超,顾达民.超声引导下前锯肌平面阻滞对乳腺癌改良根治术术后肿瘤转移、复发的影响[J].临床检验杂志(电子版),2020,9(01):117-118. [9] Knudsen K,Beckman Suurküla M,Blomberg S,et al. Central nervous and cardiovascular effects of i.v. infusions of ropivacaine, bupivacaine and placebo in volunteers.[J]British Journal of Anaesthesia,1997,78(5):507-514. [10] 夏明,王少华,童建华,等.不同浓度罗哌卡因对乳腺癌 MCF-7 细胞增殖和细胞周期的作用研究[J].临床麻醉学杂志,2016,32(07):680-683.


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