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LABA/LAMA /ICS 固定剂量组合在中重度慢阻肺稳定期治疗的研究进展

郭 晋兰, 李 欣, 邵 润玉
1、陕西省延安市延安大学附属医院 陕西 延安 716099张彩莲陕西省延安市延安大学附属医院 陕西 延安 716099
2、陕西省延安市延安大学附属医院 陕西 延安 716099

摘要


目的:慢性阻塞性肺疾病(COPD)被定义为不完全可逆的气流阻塞,并伴有持续的呼吸道症状,包括呼吸困难、咳嗽和多痰。在全球均有较高的发病率和死亡率,造成巨大的经济和社会负担,所以预防急性加重和住院是治疗策略的主要目标,但仍是一项未满足的重大需求。LABA/LAMA /ICS 固定剂量组合即长效β受体激动剂 (LABA)、长效胆碱能拮抗剂(LAMA)与吸入皮质类固醇(ICS)的联合疗法,是近几年国内外对中重度慢阻肺稳定期治疗的研究热点。本文对 LABA/LAMA /ICS 固定剂量组合治疗中重度慢阻肺稳定期的研究进展进行综述。

关键词


慢性阻塞性肺疾病;三联疗法;ICS、LABA、LAMA。

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参考


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DOI: http://dx.doi.org/10.12361/2661-3603-04-09-103064

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