Elabela在慢性肾脏病中的作用及机制研究进展

韩 维雪, 朱 之胡, 尹 凤仙, 崔 镇花
延边大学附属医院肾内科 133000

摘要

目的：近年来，慢性肾脏病的发病率逐年增加，因其病程长，并发症及合并症多，容易进展为终末期肾脏病，已经成为全世界的公共卫生 问题之一。Elabela是血管紧张素Ⅱ1型受体相关蛋白（APJ）的新型内源性配体，可以通过抵抗炎症和氧化应激、拮抗肾素-血管紧张素系 统（RAS）、改善内皮功能障碍、抑制纤维化等作用保护肾脏。

关键词

Elabela；慢性肾脏病；高血压肾病；糖尿病肾病；

参考

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