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TIMP3/MMP9/CMYC在HR-HPV持续感染致宫颈病变的研究

耿 逸凡, 郑 寰宇
华北理工大学 河北唐山 063000

摘要


目的:在全球妇女中宫颈癌是位列第四的常见的恶性疾病,同时也是发展中国家位列第二的常见癌症。人乳头瘤病毒为其非常重要的致病因素,此外明胶酶B(mmp9)、金属蛋白酶组织抑制剂3(TIMP3)、c-myc在宫颈癌的发生发展中起着重要作用。由于我国的医疗条件发展越来越好,宫颈病变的检出人数越来越多,严重影响了患者的生活质量和工作状态。本文将对明胶酶B(mmp9)金属蛋白酶组织抑制剂3(TIMP3)、c-myc在宫颈病变中的作用予以阐述。

关键词


宫颈病变;明胶酶B(mmp9);金属蛋白酶组织抑制剂3(TIMP3)、c-myc;发病机制。

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参考


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DOI: http://dx.doi.org/10.12361/2661-3603-05-04-119135

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