lncRNA在妊娠期糖尿病并发子痫前期中的研究进展

姚春 凤1, 郭秀 芳2, 宋志 慧3
1.华北理工大学研究生院 河北唐山 063000；1.唐山市工人医院 河北唐山 063000；2.滦州市人民医院 河北唐山 063000；3.华北理工大学附属唐山市妇幼保健院 河北唐山 063000

摘要

目的：妊娠期糖尿病、子痫前期均是妊娠期特有的疾病，若血糖、血压异常不能及早发现将对孕妇及胎儿造成危害。随着妊娠月份的增大，有一部分妊娠期糖尿病孕妇将会进展为子痫前期，一旦进展为子痫前期，对母儿危害更大，甚至危及生命。长链非编码RNA（longnon-codingRNA，lncRNA）是近年来研究的热点之一，lncRNA在胎盘中的异常表达可导致孕妇发生妊娠期糖尿病、子痫前期、妊娠期糖尿病并发子痫前期，那么研究lncRNA在胎盘中的异常表达以期为临床早期发现并发子痫前期的妊娠期糖尿病高危患者提供参考。

关键词

lncRNA；妊娠期糖尿病；子痫前期

参考

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