甘油三酯-葡萄糖指数与老年心力衰竭的相关性分析

赵 亚楠, 张 桂彬, 魏 宇涵, 吴 雨晴, 扈 家源, 董 博华, 包 乐, 杨 文琦
华北理工大学附属医院心内科 河北唐山 063000

摘要

目的：探讨甘油三酯-葡萄糖（TyG）指数与老年心力衰竭的相关性。方法：连续收集 2022 年 3 月～9 月就诊于华北理工大学附属医院心内科并依据《2018 中国心力衰竭诊断和治疗指南》诊断为心力衰竭的老年患者设为病例组（n=104），将同期健康体检的老年人设为对照组（n=105），比较两组的临床基线资料、TyG 指数水平的差异。采用单因素及多因素 Logistic 回归分析 TyG 指数与老年心力衰竭的关系。采用受试工作者曲线（ROC）评估 TyG 指数对老年心力衰竭的诊断价值，并确定最佳诊断界值。结果：单因素分析显示，与对照组相比，病例组 TyG 指数水平明显升高，差异具有统计学意义（P＜0.05），此外病例组在高密度脂蛋白胆固醇（HDL-C）、甘油三酯（TG）、空腹血糖（FDG）、肌酐、N 末端 B 型脑钠肽前体（NT-proBNP）、左室射血分数（LVEF）值水平、高血压病、糖尿病比例上较对照组相比均具有统计学意义（P＜0.05）。多因素非条件 Logistic 回归分析模型显示：TyG 指数（OR=4.068）、糖尿病（OR=3.859）、NT-proBNP 水平（OR=1.006）增加/升高及左室射血分数（OR=0.838）均是发生老年心力衰竭的独立危险因素。TyG 指数对预测老年心力衰竭发生的曲线下面积为 0.824（95％CI：0.768～0.879，P＜0.05），最佳诊断值为 9.04，敏感度为 73.1％，特异度为 78.1％。结论：TyG 指数与老年心力衰竭的发病呈正相关，发病时 TyG 指数水平升高，且 TyG 指数对老年心力衰竭的发生具有一定的诊断价值

关键词

关键词：甘油三酯-葡萄糖指数；心力衰竭；老年

参考

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