重组人促红细胞生成素在骨髓增生异常综合征贫血治疗的研究进展

麦迪 乃·, 娜迪 热·, 石雨 薇*
新疆医科大学第二附属医院 新疆乌鲁木齐 830000

摘要

目的：骨髓增生异常综合征(MDS)是异质的克隆性疾病，骨髓红系异常造血和红细胞生成减少是 MDS 早期的特征。超过三分之二的 MDS 患者诊断时存在贫血，改善贫血从而延缓生存时间和提高生活质量是 MDS 患者的治疗目标。二十多年来，重组人促红细胞生成素被用于 MDS患者贫血中，并取得了很好的治疗效果和临床经验。本综述中，介绍了 EPO 的分子结构及功能，EPO 在 MDS 中的机制，以及 rHuEPO 在MDS 贫血治疗中的进展。

关键词

关键词：骨髓增生异常综合征；促红细胞生成素；重组人促红细胞生成素

参考

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