HP 感染与冠状动脉粥样硬化性心血管疾病关系的研究进展

张 晨1, 严金 龙2
1.新疆医科大学第二临床医学院 乌鲁木齐 830054 2.新疆医科大学第七临床医学院 乌鲁木齐 830063

摘要

摘要：幽门螺杆菌(HelicobacterPylori，HP)感染是我国常见的慢性感染性疾病.且它的高感染率已渐渐成为一个在全球范围性受瞩目的医学问
题。冠状动脉粥样硬化性心脏病是指由于冠状动脉粥样硬化使冠状动脉管腔狭窄或闭塞导致心肌缺血、缺氧或坏死从而引发的心脏病，统
称为冠状动脉性心脏病或冠状动脉疾病，简称冠心病。近几年来有大量研究表明心血管疾病的发生发展与 HP 感染有关，本篇综述旨在说
明 HP 与冠心病的关系，以及 HP 可能通过影响血脂代谢、炎症反应、血管内皮损伤、血栓形成以及其它肠外疾病等因素，促进动脉粥样硬
化的发生与发展。

关键词

关键词：幽门螺杆菌；冠状动脉粥样硬化性心血管疾病；血脂代谢；炎症反应；血管内皮损伤；血栓形成；血浆致动脉粥样硬化指数

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作者简介：张晨，男，硕士研究生在读，研究方向：心血管疾

病

通讯作者：严金龙，男性，主任医师，副教授，研究方向：心

血管疾病 ，E-mail：[e-mail]