儿童癫痫药物治疗现状分析
摘要
药物治疗为主,早期选择合适药物有效控制患儿癫痫发作至关重要,本文就目前儿童癫痫常用药物从其机制、疗效及安全性方面做一阐述,以
期为临床治疗提供一定参考。
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[1]VOSSLER D G, WEINGARTEN M, GIDAL B E. Summary of
Antiepileptic Drugs Available in the United States of America:
WORKING TOWARD A WORLD WITHOUT EPILEPSY [J]. Epilepsy
currents, 2018, 18(4 Suppl 1): 1-26.
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[2]WANG Y, CHEN Y B, ZHANG Y Q, et al. Oxcarbazepine oral
suspension in pediatric patients with partial seizures and/or generalized
tonic-clonic seizures: a multi-center, single arm, observational study in
China [J]. World journal of pediatrics : WJP, 2017, 13(6): 551-9.
[3]SUO G H, ZHENG Y Q, WU Y J, et al. Effects of levetiracetam
and oxcarbazepine monotherapy on intellectual and cognitive
development in children with benign epilepsy with centrotemporal spikes
[J]. Acta neurologica Belgica, 2021, 121(5): 1265-73.
[4]GENG H, WANG C. Efficacy and safety of oxcarbazepine in the
treatment of children with epilepsy: a meta-analysis of randomized
controlled trials [J]. Neuropsychiatric disease and treatment, 2017,
13(685-95.
[5]JOHANNESSEN C U, JOHANNESSEN S I. Valproate: past,
present, and future [J]. CNS drug reviews, 2003, 9(2): 199-216.
[6]GUERRINI R, GENTON P. Epileptic syndromes and visually
induced seizures [J]. Epilepsia, 2004, 45 Suppl 1(14-8.
[7]NANAU R M, NEUMAN M G. Adverse drug reactions induced
by valproic acid [J]. Clinical biochemistry, 2013, 46(15): 1323-38.
[8]WU T, IDO K, OHGOH M, et al. Mode of seizure inhibition by
sodium channel blockers, an SV2A ligand, and an AMPA receptor
antagonist in a rat amygdala kindling model [J]. Epilepsy research, 2019,
154(42-9.
[9]ABDELMESIH S K, ELKHATEEB N, ZAKARIA M, et al. Initial
levetiracetam versus valproate monotherapy in antiseizure medicine
(ASM)-naïve pediatric patients with idiopathic generalized epilepsy with
tonic-clonic seizures [J]. Seizure, 2021, 91(263-70.
[10]FALSAPERLA R, SCALIA B, GIUGNO A, et al. Treating the
symptom or treating the disease in neonatal seizures: a systematic review
of the literature [J]. Italian journal of pediatrics, 2021, 47(1): 85.
[11]ARICAN P, GENCPINAR P, CAVUSOGLU D, et al.
Levetiracetam monotherapy for the treatment of infants with epilepsy [J].
Seizure, 2018, 56(73-7.
[12]WILSON S M, KHANNA R. Specific binding of lacosamide to
collapsin response mediator protein 2 (CRMP2) and direct impairment of
its canonical function: implications for the therapeutic potential of
lacosamide [J]. Molecular neurobiology, 2015, 51(2): 599-609.
[13]FARKAS V, STEINBORN B, FLAMINI J R, et al. Efficacy and
tolerability of adjunctive lacosamide in pediatric patients with focal
seizures [J]. Neurology, 2019, 93(12): e1212-e26.
[14]LI K Y, HUANG L C, CHANG Y P, et al. The effects of
lacosamide on cognitive function and psychiatric profiles in patients with
epilepsy [J]. Epilepsy & behavior : E&B, 2020, 113(107580.
[15]GUL A, MEHREEN S. Effectiveness of Lacosamide on everyday
cognitive deficits, psychiatric symptoms and resilience in patients with
epilepsy [J]. JPMA The Journal of the Pakistan Medical Association,
2020, 70(9): 1611-5.
第一作者:何金月 女 回族 1997 年 10 月 安徽滁州 研究生
通讯作者:张静 女 汉族 1980 年 10 月 河北唐山 研究生
DOI: http://dx.doi.org/10.12361/2661-3603-05-16-144100
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