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心血管代谢性危险因素在过敏性及非过敏性哮喘中的研究现况

艾克 丹木, 努尔 阿米, 韩利 梅*
新疆医科大学第二附属医院 新疆乌鲁木齐 830000

摘要


摘要:支气管哮喘(bronchi alasthma,BA)是常见的慢性气道炎症性疾病,在成人呼吸系统疾病中较为常见,哮喘临床表现广泛,影响着全世界3亿多患者[1]。全球哮喘防治创议(GlobalInitiativeforAsthma,GINA)将支气管哮喘定义为一种异质性疾病,主要以反复发作的临床症状,如喘息、气短、胸闷和咳嗽、气流受限、气道高反应性及气道炎症反应为特征[2],其常见表型为过敏性哮喘与非过敏性哮喘,二者间区别主要在于患者对变应原刺激的反应。然而,哮喘和CVD(Cardiovasculardisease,CVD)之间的关系越来越密切,共同特点是慢性全身炎症的持续存在,这最终导致控制不良的哮喘和动脉粥样硬化或缺血性心血管疾病[3]。了解哮喘和心血管风险因素之间的关联对于判断哮喘的病情、预后及治疗效果,能为临床上个体化地治疗哮喘提供重要依据。现就心血管代谢性危险因素在不同表型哮喘中的研究进展予以综述。

关键词


关键词:过敏性哮喘;非过敏性哮喘;心血管代谢性危险因素

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参考


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DOI: http://dx.doi.org/10.12361/2661-3603-05-18-145504

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