基于表面的形态学测量方法在神经退行性疾病中的研究进展

张 树贤, 郝 璐*
新疆医科大学第二附属医院 医学影像中心 乌鲁木齐 830000

摘要

摘要：基于表面形态学测量方法(surface-basedmorphometry，SBM)是一种MRI分析方法，通过对脑结构磁共振影像（Structuralmagneticresonanceimaging，sMRI）数据进行一系列计算，最终获得目标脑区的皮层灰质信息，包括厚度(Corticalthickness，CT)、脑沟深度(Sulcaldepth，SD)、沟回指数(Gydficationindex,GI)、分形维数(Fractaldimension，FD)等大脑表面形态学的量化参数。这些参数可以反映生理病理状态下大脑皮质形态的细微改变，为医生和科研人员提供一个简便直观的途径，更好了解大脑正常神经生物学过程及疾病发生发展过程中的脑皮质形态变化。本文意在介绍SBM，并综述其在神经退行性疾病中的研究现状。

关键词

关键词：SBM；神经退行性疾病；基于表面的形态学测量方法

参考

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