脑源性神经营养因子在妊娠期疾病中的研究进展

郭秀 芳1, 董春 梅2, 赵丹 3（, 宋志 慧4

摘要

摘要：脑源性神经营养因子(BDNF)自Barde及其合作者从猪脑中纯化并鉴定后,BDNF被发现与许多不同功能以及疾病有关，BDNF功能失调尤其在肥胖、焦虑、抑郁和神经退行性疾病等疾病中具有许多意义。新近研究发现,多种妊娠合并症与BDNF相关,反向添加BDNF可减轻相关疾病的病理变化,改善新生儿结局,提示BDNF可能是治疗妊娠期疾病的潜在靶点。本文结合相关最新文献,围绕BDNF在妊娠期疾病及新生儿结局的研究现状进行综述。

关键词

关键词：脑源性神经营养因子；妊娠期疾病；妊娠期糖尿病

参考

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