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Periostin在妇科肿瘤中的最新研究进展

王春 梅1, 刘会 玲3
1.甘肃中医药大学 甘肃兰州 730000 2.青海红十字医院 青海西宁 810000 3.甘肃省人民医院 甘肃兰州 730000

摘要


摘要:Periostin是一种细胞外基质蛋白,在人体多种组织器官中都有表达,通过多种细胞因子和信号通路参与机体生理和病理的调节过程。近年来,Periostin被证实在女性生殖系统中发挥着重要作用。同时,Periostin在子宫内膜癌、宫颈癌、卵巢癌的侵袭转移中发挥着重要的作用。本文对Periostin在妇科肿瘤中表达及作用进行系统综述。

关键词


关键词:Periostin;宫颈癌;子宫内膜癌;卵巢癌;宫颈癌

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参考


[1]TakeshitaS,KikunoR,TezukaK,etal.Osteoblast-specific factor 2: cloning of a putative bone adhesion protein with homology with the insect protein fasciclin I[J].BiochemJ,1993,294(Pt1):271-278.[2]TurczynA,PanczykTomaszewskaM.Theroleofperiostininkidneydisease[J].CentEurJImmunol,2021,46(4):494-501.[3]SonnenbergRiethmacherE,MieheM,RiethmacherD.PeriostininAllergyandInflammation[J].FrontImmunol,2021,12:722170.[4]KudoA.The Structure of the Periostin Gene, Its Transcriptional Control and Alternative Splicing, and Protein Expression[J].Advances in Experimental Medicine and Biology,2019,1132:7-20.[5]Panchamanon P,Pavasant P,Leethanakul C. Periostin plays role in force-induced stem cell potential by periodontal ligament stem cells: Periostin in force-induced PDLSC potential[J].Cell biology international,2019,43(5):506-515.[6]Landry NM, Cohen S, Dixon IMC. Periostin in cardiovascular disease and development: a tale of two distinct roles[J].Basic Res Cardiol,2018,113(1):1.[7]Gonzalez-GonzalezL,AlonsoJ.Periostin: A Matricellular Protein With Multiple Functions in Cancer Development and Progression[J].Frontiers in Oncology,2018,8:225.[8]WallaceDP.Periostininthekidney[J].AdvExpMedBiol,2019,1132:99-112.[9]MatsumotoH.Rolesofperiostininasthma[J].AdvExpMedBiol,2019,1132:145159.[10]Tomaru A, Kobayashi T, Hinneh JA, et al. Oligonuceotide-targeting periostin ameliorates pulmonaryfibrosis[J].GeneTher,2017,24(11):706-716.[11]LiuY,HuangZ,CuiD,etal.Themultiaspectfunctionsofperiostinintumorprogression[J].AdvExpMedBiol,2019,1132:125-136.[12]HanX,Wang Q,Wang Y,etal.Longnon-coding RNA metastasis-associated lung adenocarcinoma transcript 1/microRNA-202-3p/periostinaxis modulatesinvasionand epithetlial-mesenchymaltransitionin humancervicalcancer [J].JCellPhysiol,2019,234(8):14170-14180.[13]YamatoH,KimuraK,FukuiE,etal.Periostinsecretedby activated fibroblasts in idiopathic pulmonaryfibrosispromotestumorigenesisofnon-smallcelllungcancer[J].SciRep,2021,11(1):21114.[14]Wei WF,Chen XJ,Liang LJ,etal. Periostin+cancerassociatedfibroblasts promotelymph node metastasis by impairing the lymphatic endothelial barriers in cervical squamouscellcarcinoma[J].MolOncol,2021,15(1):210-227.[15]SueyamaT,KajiwaraY,MochizukiS,etal.Periostinasa keymoleculedefiningdesmoplasticenvironmentincolorectal cancer[J].VirchowsArch,2021,478(5):865-874.[16]ChuL,Wang F,Zhang W,etal.Periostinsecreted by carcinoma-associatedfibroblastspromotesovariancancercell platinumresistancethroughthePI3K/Aktsignalingpathway[J].Technol Cancer Res Treat, 2020,19:1533033820977535.[17]ZhongH,LiX,ZhangJ,etal.Overexpressionofperiostin ispositivelyassociatedwithgastriccancermetastasisthrough promoting tumor metastasis and invasion[J]. J Cell Biochem,2019,120(6):9927-9935.[18]MaY,HeL,ZhaoX,etal.Proteaseactivatedreceptor2 signalingpromotesself-renewaland metastasisincolorectal cancerthroughbeta-cateninandperiostin[J].CancerLett,2021,521:130-141.[19]KohSJ,Kim JW,Kim BG,etal.Matricellularprotein periostinpromotescolitis-associatedcolontumorigenesisin mice[J].Carcinogenesis,2019,40(1):102-111.[20]YuB,WuK,WangX,etal.Periostinsecretedbycancer-associatedfibroblastspromotescancerstemnessinheadand neckcancerbyactivatingproteintyrosinekinase7[J].Cell DeathDis,2018,9(11):1082.[21]TangM,LiuB,Bu X,etal.Cross-talkbetweenovarian cancercellsand macrophagesthrough periostin promotes macrophagerecruitment[J].CancerSci,2018,109(5):1309-1318.[22]Hu WW,Chen PC,ChenJM,etal.Periostin promotes epithelial-mesenchymaltransition viathe MAPK/miR-381 axisinlungcancer[J].Oncotarget,2017,8(37):62248-62260.[23]ChuanyuS,YuqingZ,ChongX,etal.Periostinpromotes migrationandinvasionofrenalcellcarcinomathroughthe integrin/focal adhesion kinase/c-Jun N-terminal kinase pathway [J]. Tumour Biol, 2017,39(4):1010428317694549.[24]Sung PL,Jan YH,Lin SC,etal.Periostinin tumor microenvironmentis associated with poor prognosis and platinum resistance in epithelial ovarian carcinoma [J]. Oncotarget,2016,7(4):4036-4047.[25]Sterzynska K, Kazmierczak D, Klejewski A, et al. Expressionofosteoblast-specificfactor2 (OSF2,periostin)isassociatedwithdrugresistanceinovariancancercelllines[J].IntJMolSci,2019,20(16):3927.[26]Ryner L,Guan Y,Firestein R,etal.Upregulation of periostin and reactive stromais associated withprimarychemoresistanceandpredictsclinicaloutcomesinepithelial ovariancancer[J].ClinCancerRes,2015,21(13):2941-2951.[27]Rojas-PuentesL,CardonaAF,CarranzaH,etal.Epithelial -mesenchymaltransition,proliferation,andangiogenesisin locallyadvancedcervicalcancertreatedwithchemoradiotherapy[J].Cancermedicine,2016,5(8):1989-1999.[28]HanX,WangQ,WangY,etal.Longnon-codingRNAme- tastasis-associatedlungadenocarcinomatranscript1/microRNA-202-3p/periostinaxismodulatesinvasionandepithelialmesenchymaltransitioninhumancervicalcancer[J].JCell Physiol,2019,234(8):14170-14180.[29]WeiWF,ChenXJ,LiangLJ,etal.Periostin+cancerassociatedfibroblastspromotelymphnodemetastasisbyimpairingthelymphaticendothelialbarriersincervicalsquamouscellcarcinoma[J].MolOncol,2021,15(1):210-227.[30]KudoA.TheStructureofthePeriostinGene,ItsTranscriptionalControlandAlternativeSplicing,andProteinExpression[J].AdvExpMedBiol,2019,1132:7-20.[31]YuY,TanCM,JiaYY.ResearchstatusandtheprospectofPOSTNinvarioustumors[J].Neoplasma,2021,68(4):673-682.[32]MalanchiI,SantamariaMartinezA,SusantoE,etal.Interactionsbetweencancerstemcellsandtheirnichegovernmetastaticcolonization[J].Nature,2011,481(7379):85-89.[33]GiannoneG,AttademoL,ScottoG,etal.EndometrialCancerStemCells:Role,CharacterizationandTherapeutic Implications[J].Cancers,2019,11(11):1820.[34]苏萍萍,施琦蓉,陈少蓉,等.periostin 促进 Ishikawa子宫内膜癌肿瘤干细胞的增殖和侵袭[J].现代妇产科进展,2020,29(06):409-415.[35]柯毓敏,周云清,吴珠娜.骨膜蛋白在子宫内膜癌的肿瘤干细胞中裸鼠成瘤性的实验研究[J].中国临床药理学杂志,2015,31(23):2329-2332.[36]UnuvarS,MelekogluR,TurkmenNB,etal.Comparisonofpreoperativeserumneopterin,periostin,indoleamine2,3-dioxygenase,YKL-40,andtenascin-Clevelswithcurrenttumormarkersforearly-stageendometrialcancer[J].IntJ GynaecolObstet,2021155(3):417-424.[37]杨莉,李新敏.Periosti 对卵巢癌腹腔转移作用的研究[J].中国妇幼保健,2016,31(19):4051-4053.[38]YueH,LiW,ChenR,etal.StromalPOSTNinducedbyTGFbeta1facilitatesthemigrationandinvasionofovarian cancer[J].GynecolOncol,2021,160(2):530-538.[39]KujawaK A,Zembala-NozyńskaE,CortezAJ,etal.Fibronectinand Periostinas Prognostic Markersin Ovarian Cancer[J].Cells,2020,9(1):149.[40]SterzyńskaK,KazmierczakD,KlejewskiA,etal.ExpressionofOsteoblast-SpecificFactor2 (OSF-2,Periostin)IsAssociatedwithDrugResistanceinOvarianCancerCellLines [J].Internationaljournalof molecularsciences,2019,20(16):3927.[41]ChuL,WangF,ZhangW,etal.PeriostinSecretedbyCarcinomaAssociatedFibroblastsPromotesOvarianCancerCellPlatinumResistanceThroughthePI3K/AktSignalingPathway[J].Technologyincancerresearch &treatment,2020,19:1079245183.[42]Tomaru A, Kobayashi T, Hinneh JA, et al. Oligonucleotide-targeting periostin ameliorates pulmonary fibrosis[J].Gene Ther,2017,24(11):706-716.[43]Zhang T, Ma G, Zhang Y,et al. miR-599 inhibits proliferationandinvasionofgliomabytargetingperiostin[J]. BiotechnolLett,2017,39(9):1325-1333.[44]MitamuraY,MuraiM,MitomaC,etal.NRF2activation inhibits both TGF-beta1- and IL-13-mediated periostin expressionin fibroblasts:benefit of cinnamaldehyde for antifibrotictreatment[J].Oxid Med CellLongev,2018:2475047




DOI: http://dx.doi.org/10.12361/2661-3603-06-05-158219

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