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妊娠期糖尿病并发子痫前期相关lncRNA的研究进展

蔡苗 苗1, 宋志 慧2, 宋丹 丹1, 柴金 杰1, 姚春 凤3, 郑婷 华2
1.华北理工大学 河北唐山 063000;2.唐山市妇幼保健院 河北唐山 063000;3.唐山工人医院 河北唐山 063000

摘要


摘要:妊娠期糖尿病和子痫前期均为妊娠期特有的疾病,容易导致多种不良妊娠结局的发生,因此其诊断和尽早干预对避免不良妊娠结局很重要。长链非编码RNA(LncRNA)是一类不编码蛋白的RNA,但其在基因表达调控方面发挥重要作用,妊娠期糖尿病和子痫前期的发病机制尚无定论,本文对各种lncRNA分型在妊娠期糖尿病和子痫前期孕妇胎盘组织中的差异表达及调控机制进行分析,协助从基因层面了解其对疾病的发生发展的影响。

关键词


关键词:娠期糖尿病;子痫前期;lncRNA;基因表达

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参考


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DOI: http://dx.doi.org/10.12361/2661-3603-06-06-159824

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