肝癌切除术后患者早期复发危险因素的研究进展
摘要
治疗难预后差。通过查找文献,总结肝癌切除术后患者早期复发的独立危险因素,如:血清甲胎蛋白≥400ng/mL、外周血中心粒细胞与淋
巴细胞比>2.215、血清HBV-DNA水平升高、肿瘤总积>65.5cm3等。通过加强对高危因素患者的观察随访,积极综合治疗,提高肝癌切除
术后患者生存质量。
关键词
全文:
PDF参考
1.DongYJ,PierreH,JGG,etal.Aglobalviewofhepatocellular
carcinoma:trends,risk,preventionandmanagement.[J].Naturereviews.
Gastroenterology&hepatology,2019,16(10):589-604.
2.胡继科,李雪梅,张凡,等.肝癌术后复发危险因素影响研究
进展[J].中华肝胆外科杂志,2018,24(9):644-648.
3.ChongCCN,WongGLH,LaiPBS.Impactofantiviraltherapyon
post—hepatectomyoutcomeforhepatitisB-relatedhepatocellular
carcinoma[J].WoddJGastmenteml,2014,20(20):6006-6012.
4..MarreroJA,FengZ,WangY,etal.Alpha-fetoprotein,
des-gammacarboxyprothrombin,andlectin-boundalpha-fetoproteinin
earlyhepatocellularcarcinoma[J].Gastroenterology,2009,137(1):
110-118.
5..MaW,WangH,TengL.Correlationanalysisofpreoperative
serumalpha-fetoprotein(AFP)levelandprognosisofhepatocellular
carcinoma(HCC)afterhepatectomy[J].2013,11:212.
6.刘孝高,赖嘉文,张相森.血清AFP表达水平在肝癌术后早期复
发中的预测价值研究[J].黑龙江医学,2020,44(07):877-879.
7.杨针.术前血清AFP水平与肝细胞肝癌术后早期复发的相关
性分析[D].中国人民解放军空军军医大学,2018.
8.TabrizianP,JibaraG,ShragerB,etal.Recurrenceof
hepatocellularcancerafterresection:patterns,treatments,and
prognosis[J].AnnSurg.2015;261(5):947-955.
doi:10.1097/SLA.0000000000000710
9.中国临床肿瘤学工作委员会,中国临床肿瘤学会(CSCO)原发
性肝癌诊疗指南,人民卫生出版社,2020
10.盛若凡,金开璞,陈旭晓,等.巴塞罗那0期肝细胞癌患者
(下转第16页)
临床研究
16
医学研究
(上接第14页)
术后肝内复发危险因素[J].中华肝胆外科杂志,2018,(12):793-796.
11.HungIF,WongDK,PoonRT,etal.RiskFactorsand
Post-ResectionIndependentPredictiveScorefortheRecurrenceof
HepatitisB-RelatedHepatocellularCarcinoma[J].PLoSOne,
2016,11(2):e0148493.
12.XuX,ChenJ,WangF,etal.RecurrenceofHepatocellular
CarcinomaAfterLaparoscopicHepatectomy:RiskFactorsandTreatment
Strategies[J].JLaparoendoscAdvSurgTechA,2017,27(7):676-684.
13.施显茂.乙肝相关性肝癌BCLC-A期患者术后早期复发转
移的危险因素分析[D].广西医科大学,2019.
14.何朝滨,林小军.中性粒细胞/淋巴细胞比值血小板/淋巴细
胞比值与TACE治疗肝癌患者预后的相关性.中国肿瘤临床,2017,
44(6):283-288.
15.袁琳.HBV相关性肝癌术后肿瘤复发预测模型的建立及评
估[D].南方医科大学,2015.
16.袁琳,万磊,陈佳佳,刘建军,阚和平,谭永法.术前TTV、NLR及
HBV-DNA定量对预测肝癌术后复发的价值[J].现代消化及介入诊
疗,2015,20(02):99-102.
17.GalunD,BogdanovicA,DjokicKovacJ,etal.Preoperative
neutrophil-to-lymphocyteratioasaprognosticpredictorafter
curative-intentsurgeryforhepatocellularcarcinoma:experiencefroma
developingcountry.CancerManagRes.2018;10:977-988.Published
2018May4.doi:10.2147/CMAR.S161398
18.Arai,K.,Fukumoto,T.,Kido,M.etal.Preoperative
neutrophil-to-lymphocyteratioasapredictorofsurvivalafterreductive
surgerypluspercutaneousisolatedhepaticperfusionforhepatocellular
carcinoma:aretrospectiveanalysis.SurgToday47,385-392(2017).
https://doi.org/10.1007/s00595-016-1384-7
19.HazemM.Zakaria,MahmoudM,etal.Totaltumorvolumeasa
prognosticvalueforsurvivalfollowingliverresectioninpatientswith
hepatocellularcarcinoma.Retrospectivecohortstudy,
AnnalsofMedicineandSurgery[J].2020,54:47-53,
https://doi.org/10.1016/j.amsu.2020.04.001.
20.王译斌,廖锦堂,谢璐璐,等.术前超声检查对肝癌切除术后早
期复发因素的预测价值[J].临床肝胆病杂志,2015,31(12):2061-2065.
21.AkamatsuN,CilloU,CucchettiA,etal.Surgeryand
HepatocellularCarcinoma.LiverCancer.2016;6(1):44-50.
doi:10.1159/000449344
22.牟思玉,辛洋,李天翔,等.肝细胞癌根治性切除术后复
发伴门静脉癌栓危险因素分析[J].中国实用外科杂
志,2019,39(6):610-614.
DOI: http://dx.doi.org/10.18686/yxyj.v2i9.33751
Refbacks
- 当前没有refback。