Effect of mechanical ventilation combined with budesonide suspension on pulmonary function indices in the treatment of severe asthma

Rong Fan, Wei Xiao, Weihua Hu, Wu Zhu
Jingzhou First People's Hospital

摘要

OBJECTIVE: To observe the effectiveness of different methods in the treatment of severe asthma. METHODS: Ninety patients admitted from 2020.2 to 2022.8 were divided into groups A and B, 45 patients each, and all were given basic symptomatic treatment, group A was given nebulized inhalation of budesonide suspension, group B was mechanically ventilated on the basis of group A's protocol, and the treatment was compared between groups. Results: After 3 weeks of continuous treatment, the lung function (FEV1, PEF, FEV1/FVC) levels of patients in group B were higher than those in group A, and the difference reached a significant level (P < 0.05). The incidence of adverse reactions in groups A and B was 8.89% and 6.67% respectively, which was not statistically significant (P > 0.05). Conclusion: In patients with severe asthma, early mechanical ventilation with inhalation of budesonide suspension can improve lung function more rapidly and with higher safety, and is worth promoting.

关键词

Severe asthma; mechanical ventilation; budesonide; lung function; adverse effects

参考

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