睡眠剥夺对个体执行功能的影响研究进展

李 炳奇, 王 艳香, 董 昊天
西藏大学

摘要

睡眠剥夺是指环境或自身无法满足正常睡眠的一种状态。执行功能是包含认知灵的活性、反应抑制和工作
记忆在内的一系列高级认知过程,用于个体思维和行为的自我调节。睡眠剥夺会损害个体认知功能,包括注意、警
觉、知觉、记忆、决策等,其中,执行功能是与大脑的前额叶有关,是认知功能的重要组成部分。本文从工作记忆、
认知灵活性和反应抑制三个方面探讨了睡眠剥夺对个体执行功能的影响。

参考

[1] Brown R E , Basheer R , Mckenna J T , et al. Control

of Sleep and Wakefulness[J]. Physiological Reviews, 2012,

92(3):1087-1187.

[2] Irwin, Michael R . Why Sleep Is Important for Health:

A Psychoneuroimmunology Perspective[J]. Annual Review of

Psychology, 2015, 66(1):143.

[3] Orze-Gryglewska J . Consequences of Sleep

Deprivation[J]. International Journal of Occupational Medicine

and Environmental Health, 2010, 23(1):95-114.

[4] Tucker A M , Paul W , Gregory B , et al. Effects of

sleep deprivation on dissociated components of executive

functioning.[J]. Sleep(1):47.

[5] Chee MW, Chuah YM. Functional neuroimaging and

behavioral correlates of capacity decline in visual short-term

memory after sleep de-privation[J]. Proc Natl Acad Sci U S A,

2007, 104: 9487-9492.

[6] Kahn-Greene ET, Killgore DB, Kamimori GH, et

al. The effects of sleep deprivation on symptoms of psycho_xfffe_pathology in healthy adults[J]. Sleep Med, 2007,8:215-221

[7] Miyake A , Friedman N P , Emerson M J , et al.

The Unity and Diversity of Executive Functions and Their

Contributions to Complex “Frontal Lobe” Tasks: A Latent

Variable Analysis[J]. cogn psychol, 2000, 41(1):49-100.

[8] Harrison Y , Jones K , Waterhouse J . The influence

of time awake and circadian rhythm upon performance on a

frontal lobe task[J]. Neuropsychologia, 2007, 45(8):1966-1972.

[9] Groeger J A , Viola A U , Lo J C Y , et al. Early

Morning Executive Functioning During Sleep Deprivation Is

Compromised by a PERIOD3 Polymorphism[J]. Sleep, 2008,

31(8):1159-1167.

[10] Baddeley, Alan, D. Is Working Memory Still

Working?[J]. American Psychologist, 2001.

[11] Baddeley A . Working memory and language: An

overview[J]. Journal of Communication Disorders, 2003,

36(3):189-208.

[12] Jaeggi SM，Buschkuehl M，Perrig WJ，et al.

The con-current validity of the N-back task as a working

memorymeasure[J]. Memory，2010，18( 4) : 394-412.

[13] 彭华，贺斌，赵明霞，等 . 睡眠剥夺对健康青年

男性工作记忆的影响及莫达非尼的干预作用 [J]. 中华神经

医学杂志，2009(9）：4.

[14] 彭子伊，陈学伟，张颖，等 .36h 完全睡眠剥夺

对客体工作记忆相关电位的影响 [J]. 中国应用生理学杂

154

科研管理

2022年4卷1期

志，2020，36(6）：5.

[15] Lythe K E , Williams S , Anderson C , et al. Frontal

and parietal activity after sleep deprivation is dependent on

task difficulty and can be predicted by the fMRI response after

normal sleep[J]. Behavioural Brain Research, 2012, 233(1):62-

70.

[16] Chee M . Functional imaging of working memory

following normal sleep and after 24 and 35 h of sleep

deprivation : Correlations of fronto-parietal activation with

performance[J]. Neuroimage, 2006, 31.

[17] Habeck C , Rakitin B C , Moeller J , et al. An eventrelated fMRI study of the neurobehavioral impact of sleep

deprivation on performance of a delayed-match-to-sample

task[J]. Brain Res Cogn Brain Res, 2004, 18(3):306-321.

[18] 李美华，白学军 . 执行功能中认知灵活性发展的

研究进展 [J]. 心理学探新，2005，25(2）：35 － 38.

[19] Jersild A T. Mental set and shift. Archives of

Psychology, 1927: 89

[20] Bratzke D , Rolke B , Steinborn M B , et al. The effect

of 40 h constant wakefulness on task-switching efficiency.[J].

Journal of Sleep Research, 2010, 18(2):167-172.

[21] Heuer H , Kleinsorge T , Klein W , et al. Total sleep

deprivation increases the costs of shifting between simple

cognitive tasks.[J]. Acta Psychologica, 2004, 117(1):29-64.

[22] Couyoumdjian A , Sdoia S , Tempesta D , et al.

The effects of sleep and sleep deprivation on task-switching

performance[J]. Journal of Sleep Research, 2010, 19.

[23] Nakashima A , Bouak F , Lam Q , et al. Task

switching following 24 h of total sleep deprivation: A functional

MRI study[J]. Neuroreport, 2017, 29(2):1.

[24] 周晓林 . 执行控制：一个具有广阔理论前途和

应用前景的研究领域 [J]. 心理科学进展，2004，12(5）：

641-642.

[25] 齐建林，段丽娜，董燕，等 . 完全睡眠剥夺对

额叶反应抑制和冲突监控功能的影响 [J]. 实用预防医学，

2016，23(002）：166-169.

[26] Qi JL，Shao Y，Yang Z，et al. The effects of 43

hours of sleep deprivation on eecutive control functions: event

－ related potentials in a visual go/no go task[J]. Soc Behav

Personal，2010，38(1):29 － 42.

[27] 宋晶晶 . 睡眠剥夺影响执行功能的日周期类型差

异研究 [D]. 西南大学 .

[28] Garavan H , Ross T J , Stein E A . Right hemispheric

dominance of inhibitory control: An event-related functional

MRI study[J]. Proceedings of the National Academy of Sciences

of the United States of America, 1999, 96(14):8301-8306.