Nrf2信号通路在外阴阴道念珠菌病中致病机制的研究进展

廖 晴君
暨南大学附属第一医院

摘要

摘要：外阴阴道念珠菌病是一种由白念珠菌机会性感染引起的皮肤黏膜疾病，念珠菌的毒力因素､宿主免疫及阴道微生物群是外阴阴道念珠菌病主要的发病机制｡Nrf2信号通路是细胞抗氧化应激重要的免疫调节通路｡该文以Nrf2通路在念珠菌性阴道炎发病机制中的抗氧化应激和激活自噬作用进行综述，旨在研究Nrf2信号通路与外阴阴道念珠菌病发病机理间的关系，有望为外阴阴道念珠菌病精准治疗提供新的研究方向｡

关键词

关键词：Nrf2信号通路;外阴阴道念珠菌病;白念珠菌;致病机制

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